{"id":2280,"date":"2018-12-13T17:05:54","date_gmt":"2018-12-13T14:05:54","guid":{"rendered":"https:\/\/www.powerterapi.com\/?p=2280"},"modified":"2018-12-13T17:05:54","modified_gmt":"2018-12-13T14:05:54","slug":"acute-effects-of-grayanotoxin-in-rhododendron-honey-on-kidney-functions-in-rats","status":"publish","type":"post","link":"https:\/\/www.powerterapi.com\/?p=2280","title":{"rendered":"Acute effects of grayanotoxin in rhododendron honey on kidney functions in rats."},"content":{"rendered":"<div class=\"bt_bb_wrapper\"><h3>Abstract<\/h3>\n<div class=\"\">\n<p>The aim of the study is to evaluate the acute biochemical and histological changes in rat kidneys after treatment with grayanotoxin (GTX) of rhododendron honey (RH). A total of 60 Sprague-Dawley female rats were divided into five groups of 12 rats each, one being a control group (group 1) and group 2 was treated with 0.015 mg\/kg\/bw of GTX standard preparation via intraperitoneal injection. Groups 3, 4, and 5 were given RH at doses of 0.1, 0.5, and 2.5 g\/kg\/bw, respectively, via oral gavage. Compared to the control group, significant increases were observed in glucose, blood urea nitrogen (BUN), and creatinine levels of the GTX-injected groups after 1 h. However, in low dose RH group, such an increase was not observed and had a normal appearance histologically. Therefore, low dose (1 g\/kg\/bw) of RH produces no acute adverse effects on renal functions of rats.<\/p>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Abstract The aim of the study is to evaluate the acute biochemical and histological changes in rat kidneys after treatment with grayanotoxin (GTX) of rhododendron honey (RH). A total of 60 Sprague-Dawley female rats were divided into five groups of 12 rats each, one being a control group (group 1) and group 2 was treatedLeer M\u00e1s<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.powerterapi.com\/index.php?rest_route=\/wp\/v2\/posts\/2280"}],"collection":[{"href":"https:\/\/www.powerterapi.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.powerterapi.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.powerterapi.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.powerterapi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2280"}],"version-history":[{"count":1,"href":"https:\/\/www.powerterapi.com\/index.php?rest_route=\/wp\/v2\/posts\/2280\/revisions"}],"predecessor-version":[{"id":2281,"href":"https:\/\/www.powerterapi.com\/index.php?rest_route=\/wp\/v2\/posts\/2280\/revisions\/2281"}],"wp:attachment":[{"href":"https:\/\/www.powerterapi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2280"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.powerterapi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2280"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.powerterapi.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2280"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}